Untitled

flowchart TD
    A[Ayahuasca Ingestion]
        B[Contains: DMT + MAO Inhibitors<br/>(Harmine, Harmaline, Tetrahydroharmine)]
            C[MAO Inhibition<br/>(Blocks MAO-A)]
                D[Prevents DMT Breakdown]
                    E[Active DMT Enters Circulation]
                        F[DMT Receptor Actions]
                            F1[5-HT2A Agonism<br/>&rarr; Hallucinations & Altered Perception]
                                F2[5-HT1A Agonism<br/>&rarr; Emotional/Introspective Effects]
                                    F3[Sigma-1 Activation<br/>&rarr; Neuroprotection & Neural Plasticity]
                                        F4[Glutamate Modulation<br/>&rarr; Cognitive Changes]
                                            G[Indirect Increase in<br/>Dopamine & Noradrenaline]
                                                H[Physiological Effects<br/>&rarr; ↑ Heart Rate, BP,<br/>Nausea & Vomiting]
                                                    I[Behavioral Effects<br/>&rarr; Ego Dissolution,<br/>Emotional Release,<br/>Mood Elevation]
                                                        J[Potential Role in Addiction Treatment]
                                                            J1[Explored for Substance Abuse Therapy]
                                                                J2[Other De-addiction Drugs:<br/>Methadone, Buprenorphine,<br/>Naltrexone, etc.]

                                                                    A --> B
                                                                        B --> C
                                                                            C --> D
                                                                                D --> E
                                                                                    E --> F
                                                                                        F --> F1
                                                                                            F --> F2
                                                                                                F --> F3
                                                                                                    F --> F4
                                                                                                        F1 --> H
                                                                                                            F2 --> I
                                                                                                                F3 --> I
                                                                                                                    F4 --> I
                                                                                                                        E --> G
                                                                                                                            G --> H
                                                                                                                                G --> I
                                                                                                                                    I --> J
                                                                                                                                        J --> J1
                                                                                                                                            J --> J2