sample

@echo off
setlocal enabledelayedexpansion

:: Set the path to the input file
set "inputFile=your_input_file.txt"

:: Set the path to the temporary output file
set "outputFile=temp_output_file.txt"

:: Clear output file if exists
echo.> %outputFile%

:: Read the input file line by line
for /f "usebackq delims=" %%a in ("%inputFile%") do (
    set "line=%%a"

    :: Search for the pattern
    echo.!line! | findstr /r /c:"programfolder=[A-Z\\:]*" >nul
    if !errorlevel! == 0 (
        for /f "tokens=2 delims==" %%b in ("!line!") do (
            set "folderPath=%%b"

            :: Compare with the environment variable
            if "!folderPath!" neq "%ProgramLocation%" (
                set "line=programfolder=%ProgramLocation%"
            )
        )
    )

    :: Write the line to the output file
    echo.!line! >> %outputFile%
)

:: Replace the original input file with the updated output file
move /y %outputFile% %inputFile%

endlocal